Safety and efficacy of an attenuated strain of Salmonella choleraesuis for vaccination of swine
1992
Kramer, T.T. | Roof, M.B. | Matheson, R.R.
The purpose of this study was to determine the safety and efficacy of a live Salmonella choleraesuis immunizing strain, obtained by repeated ingestion and recovery through porcine neutrophils. The strain was tested in mice and in pigs. The vaccine was safe and effective in controlled experimental trials, using clinical, pathologic, and microbiologic criteria. Vaccinated pigs were able to maintain normal weight gains during the 4-week observation period following challenge inoculation with a high dose of a virulent strain.
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书目信息
American journal of veterinary research
ISSN
0002-9645
出版者
The Royal Society of Chemistry
其它主题
Dose-response relationship; Immunologic; Prevention & control; Attenuated; Adverse effects; Swine diseases; Veterinary; Human health and safety; Salmonella enterica; Salmonella infections; Female; Bacterial vaccines
语言
英语
注释
2019-12-04
类型
Journal Article; Text
2024-02-29
MODS
