Label-free enrichment of rare unconventional circulating neoplastic cells using a microfluidic dielectrophoretic sorting device

Jose Montoya Mira; Ajay A. Sapre; Brett S. Walker; Jesus Bueno Alvarez; Kyle T. Gustafson; Eugene Tu; Jared M. Fischer; Melissa H. Wong; Sadik Esener; Yu-Jui Chiu

Label-free enrichment of rare unconventional circulating neoplastic cells using a microfluidic dielectrophoretic sorting device

2021

Montoya Mira & Sapre et al. design a microfluidic device utilizing dielectrophoresis for the enrichment of circulating neoplastic cells that possess both epithelial and immune-like characteristics. They optimized the device using in vitro models and then applied it to clinical samples for clinically relevant mutation analyses.

显示更多 [+]