Construction and activity analyses of single functional mouse peroxiredoxin 6 (Prdx6)

Wang Lu-Lu; Lu Shi-Ying; Hu Pan; Fu Bao-Quan; Li Yan-Song; Zhai Fei-Fei; Ju Dan-Di; Zhang Shi-Jun; Su Bing; Zhou Yu; Liu Zeng-Shan; Ren Hong-Lin

Construction and activity analyses of single functional mouse peroxiredoxin 6 (Prdx6)

2019

Introduction: Peroxiredoxin 6 (Prdx6) is a bifunctional protein with glutathione peroxidase activity and phospholipase A2 activity. Previous studies have shown a significant positive correlation between the intracellular survival ability of Brucella and Prdx6. Here, the Prdx6 enzyme with a single activity was constructed to facilitate study of the relationship between the single function of Prdx6 and Brucella infection.

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