Construction and activity analyses of single functional mouse peroxiredoxin 6 (Prdx6)
Wang Lu-Lu | Lu Shi-Ying | Hu Pan | Fu Bao-Quan | Li Yan-Song | Zhai Fei-Fei | Ju Dan-Di | Zhang Shi-Jun | Su Bing | Zhou Yu | Liu Zeng-Shan | Ren Hong-Lin
Introduction: Peroxiredoxin 6 (Prdx6) is a bifunctional protein with glutathione peroxidase activity and phospholipase A2 activity. Previous studies have shown a significant positive correlation between the intracellular survival ability of Brucella and Prdx6. Here, the Prdx6 enzyme with a single activity was constructed to facilitate study of the relationship between the single function of Prdx6 and Brucella infection.
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