Blastogenesis of lymphocytes by stimulation with lipopolysaccharides from Campylobacter jejuni (C.jejuni-LPS): Effect of macrophage and immunization
2013
Muto, T. (Yokohama City Institute of health, Yokohamashi, Kanagawaken (Japan))
As the addition of macrophages to mouse lymphocytes, blastogenesis of lymphocytes stimulated with C. jejuni-LPS presented a decrease in the SI value and the incorporation of 3H-TdR. From those results, the macrophages is like to work for the suppression of lymphocyte blastogenesis. The blastogenesis of lymphocytes in the immunized mice compared to mouse non-immune, the lymphocytes obtained from mice that had been immunized with live bacteria of two strains such as Y4061 and A3309 indicate the significantly higher incorporation of 3H-TdR after 3 days, and showed a high value about twice the value of SI. The immunization with C. jejuni is like to work to promote blastogenesis of lymphocytes.
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