Structure-activity studies: in vitro antileishmanial and antimalarial activities of anthraquinones from Morinda lucida.

Sittie, A. A.; Lemmich,E.; Olsen, C. E; Hviid, L.; Kharazmi,A.; Nkrumah,F. K. Christensen, S. B.

Structure-activity studies: in vitro antileishmanial and antimalarial activities of anthraquinones from Morinda lucida.

1999

Sittie, A. A.; Lemmich,E.; Olsen, C. E; Hviid, L.; Kharazmi,A.; Nkrumah,F. K. Christensen, S. B.

Anthraquinones were isolated following bioassay-guided fractionation from roots of M. lucida (collected from Ghana). Structure-activity studies showed that an aldehyde group at C-2 and a phenolic hydroxy group at C-3 enhanced the antiprotozoal activity of the anthraquinones against Plasmodium falciparum and promastigotes of Leishmania major in vitro.

Show more [+]

AGROVOC Keywords

anthraquinones chemical structure forest products fractionation ghana in vitro medicinal plants productos de la madera productos forestales produit forestier roots structure activity relationships wood products

Bibliographic information

Published in

Planta Medica. 65: 3, p259-261, 1999.

Publisher

Georg Thieme Verlag

Other Subjects

Plant composition; Produto de madeir; Produto floresta; Produit derive du bois; Gfis keywords; Gfis

Language

English

Type

Text; Journal Article; Journal Article; Journal Part

In AGRIS since: 2005-11-15

Format: AGRIS AP

Data Provider

This bibliographic record has been provided by Forestry Research Institute of Ghana

Discover this data provider's collection in AGRIS

Lookup at Google Scholar

If you notice any incorrect information relating to this record, please contact us at [email protected]

FAO AGRIS - International System for Agricultural Science and Technology

Share

Structure-activity studies: in vitro antileishmanial and antimalarial activities of anthraquinones from Morinda lucida.

1999

AGROVOC Keywords

Bibliographic information