Toxicological evaluation of magnetic ionic liquids in human cell lines

Frade, Raquel F.M.; Simeonov, Svilen; Rosatella, Andreia A.; Siopa, Filipa; Afonso, Carlos A.M.

Toxicological evaluation of magnetic ionic liquids in human cell lines

2013

Frade, Raquel F.M. | Simeonov, Svilen | Rosatella, Andreia A. | Siopa, Filipa | Afonso, Carlos A.M.

Magnetic ionic liquids (MILs) are new solvents with an interesting broad of applications however their toxicity is still an open issue. In this paper we report the toxicity of [C8MIM] and [Choline-Cn] based magnetic ionic liquids assessed in two human cell lines: normal skin fibroblasts (CRL-1502) and colorectal adenocarcinoma cells (CaCo-2), acquiring this last characteristics of human enterocytes after differentiation. The results showed that [CoCl4] and [MnCl4] are more prone to generate cytotoxicity.

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AGROVOC Keywords

adenocarcinoma cell lines chemical synthesis chemistry chlorides cobalt cytotoxicity fibroblasts humans humans manganese compounds models risk assessment solvents toxicity toxicity

Bibliographic information

Published in

Chemosphere

Volume 92 Pagination 100 - 105 ISSN 0045-6535

Publisher

Elsevier GmbH

Other Subjects

Cell survival; Drug effects; Cell line; Human cell lines; Magnetic ionic liquids; Chemical; Environmental pollutants; Ionic liquids; Enterocytes; Caco-2 cells; Magnetics; Ionic liquids

Language

English

Type

Journal Article; Text

In AGRIS since: 2024-02-28

Format: MODS

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Links

DOI DOI http://dx.doi.org/10.1016/j.chemosphere.2013.02.047

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