Toxicological evaluation of magnetic ionic liquids in human cell lines

Frade, Raquel F.M.; Simeonov, Svilen; Rosatella, Andreia A.; Siopa, Filipa; Afonso, Carlos A.M.

Toxicological evaluation of magnetic ionic liquids in human cell lines

2013

Frade, Raquel F.M. | Simeonov, Svilen | Rosatella, Andreia A. | Siopa, Filipa | Afonso, Carlos A.M.

Magnetic ionic liquids (MILs) are new solvents with an interesting broad of applications however their toxicity is still an open issue. In this paper we report the toxicity of [C8MIM] and [Choline-Cn] based magnetic ionic liquids assessed in two human cell lines: normal skin fibroblasts (CRL-1502) and colorectal adenocarcinoma cells (CaCo-2), acquiring this last characteristics of human enterocytes after differentiation. The results showed that [CoCl4] and [MnCl4] are more prone to generate cytotoxicity.

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Ключевые слова АГРОВОК

adenocarcinoma cell lines chemical synthesis chemistry chlorides cobalt cytotoxicity fibroblasts humans humans manganese compounds models risk assessment solvents toxicity toxicity

Библиографическая информация

Опубликовано в

Chemosphere

Том 92 Нумерация страниц 100 - 105 ISSN 0045-6535

Издатель

Elsevier GmbH

Другие темы

Cell survival; Drug effects; Cell line; Human cell lines; Magnetic ionic liquids; Chemical; Environmental pollutants; Ionic liquids; Enterocytes; Caco-2 cells; Magnetics; Ionic liquids

Язык

Английский

Тип

Journal Article; Text

В АГРИСе с: 2024-02-28

Формат: MODS

Поставщик данных

Эту запись предоставил National Agricultural Library

Откройте коллекцию этого поставщика данных в AGRIS

Ссылки

DOI DOI http://dx.doi.org/10.1016/j.chemosphere.2013.02.047

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