Toxicological evaluation of magnetic ionic liquids in human cell lines

Frade, Raquel F.M.; Simeonov, Svilen; Rosatella, Andreia A.; Siopa, Filipa; Afonso, Carlos A.M.

Toxicological evaluation of magnetic ionic liquids in human cell lines

2013

Frade, Raquel F.M. | Simeonov, Svilen | Rosatella, Andreia A. | Siopa, Filipa | Afonso, Carlos A.M.

Magnetic ionic liquids (MILs) are new solvents with an interesting broad of applications however their toxicity is still an open issue. In this paper we report the toxicity of [C8MIM] and [Choline-Cn] based magnetic ionic liquids assessed in two human cell lines: normal skin fibroblasts (CRL-1502) and colorectal adenocarcinoma cells (CaCo-2), acquiring this last characteristics of human enterocytes after differentiation. The results showed that [CoCl4] and [MnCl4] are more prone to generate cytotoxicity.

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Mots clés AGROVOC

adenocarcinoma cell lines chemical synthesis chemistry chlorides cobalt cytotoxicity fibroblasts humans humans manganese compounds models risk assessment solvents toxicity toxicity

Informations bibliographiques

Publié dans

Chemosphere

Volume 92 Pagination 100 - 105 ISSN 0045-6535

Editeur

Elsevier GmbH

D'autres materias

Cell survival; Drug effects; Cell line; Human cell lines; Magnetic ionic liquids; Chemical; Environmental pollutants; Ionic liquids; Enterocytes; Caco-2 cells; Magnetics; Ionic liquids

Langue

anglais

Type

Journal Article; Text

Sur AGRIS depuis: 2024-02-28

Format: MODS

Fournisseur de données

Cette notice bibliographique a été fournie par National Agricultural Library

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Liens

DOI DOI http://dx.doi.org/10.1016/j.chemosphere.2013.02.047

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