The research was performed at the Faculty of Veterinary Medicine of the Latvia University of Agriculture. At the moment the research in veterinary anaesthesia is in its infancy stage. The aim of this study was to determine the effects of the acepromazine maleate on intraocular pressure (IOP) and horizontal pupil diameter (HPD) in a dog's eye. Ten adult dogs of different age, breed and sex were examined clinically and ophthalmologically. All animals were clinically and ophthalmologically healthy. Animals received acepromazine intramuscularly. IOP and HPD were measured every 5 minutes for the total period of 60 minutes. It was established that the acepromazine maleate intramuscular injection causes an IOP decrease in booth eyes. A significant IOP decrease was observed from 35 till 60 minutes after the acepromazine injection. The pupil contraction was observed 5 minutes after the treatment and continued to contract till the end of the research. As acepromazine maleate causes a significant decrease of intraocular pressure, it is not contraindicated to be used in the case of corneal trauma, perforation, glaucoma and corneal ulcers.

The aim of this pilot study was to assess whether a single mesenchymal stem cell intra-articular injection in the osteoarthritic joint gives a therapeutic effect. This trial study was made in order to better manage and structure further study on more dogs. Single injections of 3 million mesenchymal stem cell intra-articular injections were made bilaterally in the osteoarthritic elbow joints. The dog was examined before and after monthly stem cell therapy using stance analyser scales to determine the static weight of each limb. Weight balance between forelegs improved, but not significantly (p is greater than 0.05). A radiographic examination was made for both elbow joints before stem cell therapy and the second and fifth month thereafter. Calculations of sub-trochlear sclerosis in percentage were made using mediolateral projections. Sub-trochlear sclerosis in percentage significantly decreased (p is less than 0.05) after stem cell therapy in both legs.