Acute effects of anti-inflammatory drugs on neodymium:yttrium aluminum garnet laser-induced uveitis in dogs

Millichamp, N.J.; Dziezyc, J.; Rohde, B.H.; Chiou, G.C.Y.; Smith, W.B.

Acute effects of anti-inflammatory drugs on neodymium:yttrium aluminum garnet laser-induced uveitis in dogs

1991

Millichamp, N.J. | Dziezyc, J. | Rohde, B.H. | Chiou, G.C.Y. | Smith, W.B.

Dogs were treated with flunixin meglumine, a cyclo-oxygenase inhibitor; L-651,896, a 5-lipoxygenase inhibitor; and matrine, a herbal anti-inflammatory drug. Acute inflammation was induced in the eyes by disruption of the anterior lens capsule, using a neodymium:yttrium aluminum garnet laser. Intraocular pressure, pupil diameter, and eicosanoid production in the aqueous humor were measured. Statistically significant effects were seen in the eyes of flunixin meglumine-treated dogs where mydriasis was maintained and aqueous prostaglandin E2 concentration was reduced.

Afficher plus [+]

Mots clés AGROVOC

alkaloids analysis animals chemistry diameter dogs dogs drug therapy eicosanoids etiology eyes flunixin inflammation pharmacology uveitis

Informations bibliographiques

Publié dans

American journal of veterinary research

Volume 52 Numéro 8 Pagination 1279 - 1284 ISSN 0002-9645

D'autres materias

Analogs & derivatives; Benzofurans; Anti-inflammatory agents; Laser therapy; Therapeutic use; Dinoprostone; Pupil; Lipoxygenase inhibitors; Intraocular pressure; Internal pressure; Pupil diameter; Non-steroidal; Anti-inflammatory agents; Adverse effects; Quinolizines; Matrine; Dog diseases; Clonixin; Leukotriene b4; Veterinary; Drug effects; Aqueous humor; 5-lipoxygenase inhibitors

Langue

anglais

Note

2019-12-04

Type

Text; Journal Article

Sur AGRIS depuis: 2024-02-28

Format: MODS

Fournisseur de données

Cette notice bibliographique a été fournie par National Agricultural Library

Découvrez la collection de ce fournisseur de données dans AGRIS

Consulter Google Scholar