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Complement, bacteriostatic, and enzymatic activities in sera from guinea pigs given aflatoxin and/or rubratoxin.
1989
Thurston J.R. | Sacks J.M. | Richard J.L. | Peden M. | Driftmier K.
The relationship of serum complement activity and bacteriostatic activity was investigated in male guinea pigs given aflatoxin and/or rubratoxin. In experiment 1, guinea pigs were given 0.6 mg of aflatoxin/kg of body weight, PO, once. In experiment 2, guinea pigs were given 0.02 mg of aflatoxin/kg, PO, and/or 8 mg of rubratoxin, PO, 11 times. Aflatoxin (0.02 mg/kg) had no effect given alone, but potentiated the effect of rubratoxin. In both experiments, changes in complement activity were accompanied by similar but not always significant (P less than 0.05) changes in bacteriostatic activity of serum. Guinea pigs given 0.06 mg of aflatoxin/kg had significant (P less than 0.05) changes in complement titers and in serum alkaline phosphatase, alanine aminotransferase, and aspartate aminotransferase activities. Guinea pigs given repeated oral doses of aflatoxin and/or rubratoxin had changes in complement titers, bacteriostasis, and alkaline phosphatase and aspartate aminotransferase activities, but not in alanine aminotransferase activities. Significant differences were detected only when average values for all guinea pigs given rubratoxin or rubratoxin with aflatoxin were compared with average values for guinea pigs not given rubratoxin.
Показать больше [+] Меньше [-]Controlled wound repair in guinea pigs, using antimicrobials that alter fibroplasia.
1986
Kenyon A.J. | Hamilton S.G. | Douglas D.M.
Circumoval and circumlarval precipitate reactions of Angiostrongylus cantonensis [with rats and guinea pigs]
1984
Oku, Y. | Kamiya, M. (Hokkaido Univ., Sapporo (Japan). Faculty of Veterinary Medicine)
Asymptomatic carrier state of dermatophytes on laboratory rodents and the perfect state of Trichophyton mentagrophytes isolated from albino rats
1990
Lee, H.J. | Choi, W.P. (Chungnam National University, Taejon (Korea Republic). Department of Veterinary Medicine) | Jun, M.H. (Kyungpook National University, Taegu (Korea Republic). College of Veterinary Medicine)
Virulence-associated plasmids of Yersinia species isolated from pigs and dogs in Korea
1989
Choi, W.P. (Kyongbuk National Univ., Taegu (Korea R.). Coll. of Veterinary Medicine) | Lee, H.J. (Chungnam National Univ., Taejon (Korea R.). Coll. of Agriclture) | Jung, S.C. (Rural Development Administration, Anyang (Korea R.). Veterinary Research Institute)
Nine strains of Yersinia species isolated from pigs and dogs in Korea, comprising 5 strains of Yersinia enterocolitica, 2 strains of Y. kristensenii and each strain of Y. pseudo-tuberculosis and Y. intermedia, were examined for the presence of virulence-associated plasmids, calcium dependency and provocation of guinea pig conjunctivitis (Sereny test). Three strains of Y. enterocolitica isolated from pigs were positive in calcium dependency and harbored one plasmid of about 45 megadalton, but negative in Sereny test
Показать больше [+] Меньше [-]Studies on development of Escherichia coli subunit vaccine against calf diarrhea, 2; immunogenicity and protective efficacy of Escherichia coli K99 and F41 pilus vaccines in experimental animals
1986
Kim, J.M. | Yoon, Y.D. | Park, J.M. (Rural Development Administration, Anyang (Korea R.). Veterinary Research Inst.) | Kim, B.H. (Kyongbuk National Univ., Taegu (Korea R.). Dept. of Veterinary Medicine)
The oil emulsion and alhydrogel pilli vaccines were prepared from a strain (O9: K35, K99, F41) of enterotoxigenic Escherichia coli isolated from calves with diarrhea and their immunogenicity was tested in guinea-pigs, pregnant goats and cows. Serum antibody responses to K99 and F41 antigens in guinea-pigs given experimental oil and gel vaccines peaked at 4 and 6 weeks after vaccinations. At that time, the mean hemagglutination inhibition titers to K99 and F41 antigens in guinea pigs given oil vaccine were 1:25 and 1:1,218 and those given gel vaccine were 1:54 and 1:724 respectively
Показать больше [+] Меньше [-]Immunohistochemical identification of Listeria monocytogenes antigen in tissue sections of experimentally infected rats after pretreatment with dexamethasone
1992
Sur, J.H. | Kim, S.B. (Gyeongsang Nat'l Univ., Chinju (Korea Republic). Coll. of Veterinary Medicine)
Experimental trichothecene (T-2) Toxicosis in Guinea pigs
1991
Kim, J.S. (Gyeongsang National Univ., Chinju (Korea Republic). Coll. of Veterinary Medicine) | Park, U.B. (Seoul National Univ., Suwon (Korea Republic). Coll. of Veterinary Medicine)
Chemically induced delayed cutaneous hypersensitivity in guinea pigs and rabbits experimentally infected with Mycobacterium bovis
1986
Lee, C.Y. | Lee, C.G. | Park, Y.J. (Chonnam National Univ., Kwangju (Korea R.). Dept. of Veterinary Medicine)
In order to evaluate the effects of the cell-mediated immunity of the animal in the chronic diseases the guinea pigs and rabbits were inoculated with Mycobacterium bovis. After 6 weeks these animals were sensitized and challenged with 2, 4-dinitrochlorobenzene. The cutaneous reactions observed in these animal species were similar each other. Macroscopic and microscopic responses in the animal experimentally infected with M. bovis were markedly reduced compared to those in the control animals
Показать больше [+] Меньше [-]Phytomitogen induced blast transformation of guinea pig, 1; effect of medium, phytomitogen and cell concentration on the uptake of 3H-thymidine
1986
Kim, J.S. (Kyongsang National Univ., Chinju (Korea R.). Dept. of Veterinary Medicine) | Bak, U.B. (Seoul National Univ., Seoul (Korea R.). Dept. of Veterinary Medicine)
The present study has been carried out to investigate the optimal condition on the blastogenesis of guinea pig lymphocytes. A microculture system in conjuction with a semiautomatic multiple sample harvester (SAMSH) was used to study the in vitro optimal condition of guinea pig lymphocytes. Data were presented to show many variables that were involved in studying the responses of guinea pig lymphocyte in a microculture system to the stimulation of Concanavalin A (Con A) and lipopolysaccharide (LPS)
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