Sprague-Dawley rats received subcutaneous injections of gentamicin sulfate, 50 and 100mg/kg for 3, 7 and 10 days. The hematological and blood chemical values were determined. Kidneys were examined histologically and ultrastructurally. The serum values of aspartate transaminase, blood urea nitrogen and creatinine in the rats administered gentamicin, 50 and 100mg/kg/day were significantly increased than those in the control. The ratio of kidney weight to body weight was significantly increased in the rats injected gentamicin, 100mg/kg for 10 days than those in the control

This paper described the distribution and transmissibility of BLV (bovine leukemia virus), the relationship between antibodies against BLV and lymphocyte count in 313 dairy cattle from 36 herds, the clinical signs and hematological findings of 2 lymphosarcomatous cattle in the northern area of Kyongbuk. Eighty three (26.5%) of 313 cattle from 36 herds were positive for BLV antibodies and 19 (52.8%) of 36 herds were infected with BLV by the immunodiffusion test with BLV-gp antigen. The rate of BLV infection in cattle varied from 9.5 to 87.5% in 19 positive herds, it was higher in herds pastured during summer and included lymphosarcomatous onset than the other and also higher with the age