This study was performed to clarify the clinical signs of macroscopical lesions of pigs naturally infected with hog cholera. There was clinical and macroscopical observation on the natural cases of hog cholera and experimental cases inoculated with ALD virus and isolated virus strains. In the clinical inspection of the natural cases, diarrhea (73.1%), blotching of ear (50.0), conjunctivitis (32.7%) and dyspnea (30.8%) were observed. Dyspnea, constipation and erythema of skin were observed mainly in the experimental cases, however, staggering and conjunctivitis in pigs infected with ALD virus were found and convulsion and hemorrhage of skin of pigs infected with isolated virus were seen, respectively. The gross lesions of natural cases were hemorrhage of lymph node (82.5%), pneumonia (55.0%), gastritis and hemorrhage (52.5%), cardial hemorrhage (40.0%) and renal petechiation (37.5%), while in the experimental cases, hemorrhage of lymph node, pneumonia, gastritis and hemorrhage, enteritis and hemorrhage of large intestine and splenic infarction were seen mainly

The presence of fibrinous thrombi in the blood vessels of multiple organs was observed in chickens which died within approximately 3 days post inoculation. The density of fibrinous thrombi (i.e., the number of thrombi per section) was greatest in the lung, followed by spleen, kidney, liver and heart. The cause of death of the chickens after infection with acute fowl cholera was probably due to an endotoxin (septic) shock accompanied with DIC in multiple organs

A polyvalent live Eschericia coli oral vaccine were prepared by the use of 5 field isolates of enteropathogenic E. Coli, serotypes 08: K87, K83a, b; 0138: K81, K88a, c; 0141: K85a, b, K88a, b: 0149: K91, K88a, c and 0157: K'V17' K88a, c. Some field experiments were conducted to investigate the effectiveness of the polyvalent live E. coli oral vaccine in the prevention of neandatal colibacillosis in piglets suckling orally vaccinated sows. Seventy-nine pregnant sows in and intensive pig farm were vaccinated with oral vaccine 4 weeks prior to farrowing and 19 sows were chosen for control. The piglets suckling vaccinated sows showed a significant protection against neonatal enteric colibacillosis during the 2 weeks observation period from the farrowing but no significant differences in protection between vaccinated and control group were observed with piglets older than 15 days

Pathological studies on 6 milk goats administered with urea were carried out to determine the effects of acute and chronic poisoning on the animal. Clinical signs appeared about 10 minutes after ingestion of the urea and they consisted chiefly in dullness, staggering, uncontrolled urination, dyspnoea, frothy salivation, bloating, muscular tremor, humping of back and tetanic spasms. Macroscopic lesions were failure of blood clot, frothy and bloody contents in the highly congested respiratory tract, pulmonary edema, rumenitis and abomatitis accompanying with petechiation of the upper small intestine. Microscopically, the liver showed vacuolar degeneration, fatty change and areas of necrosis and partial proliferation of the interlobular connective tissues in chronic cases. The renal epithelium displayed vacuolar degeneration, necrosis and hyaline casts in their lumens. In the lungs, there were hyperemia, edema, hemorrhages, and acute catarrhal bronchitis. Neuronal degeneration and necrosis in the central nervous system, cattarhal rumenitis, abomatitis, doudenitis and myocaridal hemorrhage were also demonstrated

3,354 fattening pigs were examined. Gross pathologic alterations of the stomach were classified as normal, with epithelial change, erosion, ulcer and scar formation. In the seasonal prevalence of gastric ulceration, severe ulceration with erosion was shown during autumn and winter, whereas mild ulceration was mainly shown during spring and summer. Of the 3,354 pigs examined, 20.7% were found to be normal. Of the rest, 40% had epithelial changes, followed by erosion (24.7%), ulcer (13.6%) and scar formation (0.9%), respectively. In the prevalence of ulcers in the different regions of the stomach, the fundic region had the highest rate (61.6%) of ulceration, followed by cardiac (21.7%), esophageal (15.0%) and pyloric region (1.7%). The principal gross changes were severe epithelial changes with keratotic proliferation in the esophageal region, and in the fundic region, severe folding of the stomach wall was covered with bloody mucous exudates. Main histopathological changes were inflammatory cell infiltrations in most cases, hemorrhages in acute ulcers and prominent proliferation of granulation tissues in chronic ulcers

This is a study of bovine viral leukosis in a young cattle (10 months old). Main clinical symptoms observed were emaciation, digestive disorder, and marked enlargement of superficial lymph nodes. Biopsied specimen of the lymph nodes revealed a characteristics histological picture of bovine leukosis. A severe degree of leukocytosis (108,000/cmm) accompanied by marked lympocytosis (96%=680/cmm) was detected from the hematological examination of peripheral blood. Most of the lymphocytes (94%=101,520) were large-sized, immature, and abnormal in their morphology. In addition, a pronounced anemia (1.78 million/cmm) without regenerative evidence of erythrocyte was noted. The serum of the patient showed positive reaction against gp antigen of bovine leukosis virus in agar gel diffusion test

This paper dealt with histopathological observations of the nephroblastoma in the pregnant pig which died 8 days before parturition day. In the necropsy findings the pregnant pig died of circulative and respiratory disturbance by compression of fetus and renal tumor weighing about 12 kg. In the microscopical findings of the renal tumor it was composed of well differentiated tumor cells and connective tissue elements. As differentiation of the neoplastic epithelial cells progressed, tubular and cystic structures, and papillary structures resembling glomeruli appeared. This tumor was regarded as nephroblastoma

An acute enteric disease accompanied with vomiting diarrhea, anorexia, pyrexia, dehydration and high mortality occurred in dogs. According to epidemiological and clinico-pathological studies the cases were tentatively diagnosed as viral enteritis and the possibility of canine parvovirus as the etiological agent for the cases was also discussed

A total of 136 dairy cows were subjected to test for bovine mastitis by AHI mastitis detector, microbiological test (MT) and California mastitis test (CMT). MT indicated that the most important causative microorganisms isolated from mastitis milk were Staphylococcus aureus (59.3%), Staphylococcus epidermidis (16.4%), Streptococcus agalactiae (12.4%) and Streptococcus uberis (4.4%). In Holstein breed, the critical threshold of electrical conductivity values of normal and mastitic milk were found to be less than 6,900 S and above, 7, 700 S, respectively. Although there was good agreement (92.0%) between AHI mastitis, the diagnostic efficiency of AHI mastitis detector (80.0%) was higher than that of CMT (74.0%) when compared with microbiological findings. In addition, handiness and objectivity of AHI mastitis detector for the detection of mastitic milk suggested that this could effectively be used for the diagnosis of both clinical and subclinical bovine mastitis in field

This experiment was conducted to compare six serological tests for diagnosing bovine brucellosis standard plate agglutination test (SPT), standard tube agglutination test (STT), complement fixation test (CFT), Rivanol test (RT), agar gel precipitation test (AGP) and counter immunoelectrophoresis (CIEP) in using 38 sera from brucella reactors and 222 sera from cattle. The SPT gave 1.6% apparent false negative reactions and 15.4% apparent false positive reactions when compared with STT which is an official test for bovine brucellosis in this country. The distribution of antibody titers determined by STT showed that 37.5% of 38 reactors had antibody titers of 400 or higher. When 38 reactors judged by STT were tested by CFT and RT, 32 cattle (82.4%) were positive by CFT and 33 catlle (86.8%) were positive by RT respectivily. This results suggest that Rt is comparable to CFT in the diagnosis of bovine brucellosis. The results also indicated that both AGP and CIEP were insensitive to detect brucella infection in cattle