Reduced excitatory neuron activity and interneuron-type-specific deficits in a mouse model of Alzheimer’s disease
2022
Moustafa Algamal | Alyssa N. Russ | Morgan R. Miller | Steven S. Hou | Megi Maci | Leon P. Munting | Qiuchen Zhao | Dmitry Gerashchenko | Brian J. Bacskai | Ksenia V. Kastanenka
Interneuron-specific lines reveal that somatostatin interneurons are hyperactive whereas pyramidal neurons and PV interneurons are ‘hypoactive’ in the APP/PS1 mouse model of Alzheimer’s Disease.
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出版者
Nature Portfolio
其它主题
Biology (general)
语言
英语
类型
Journal Article
来源
Communications Biology, Vol 5, Iss 1, Pp 1-9 (2022)
2023-03-15
AGRIS AP