Lewis acid-promoted cascade reaction for the synthesis of Michael acceptors and its application in a dimerization reaction
2017
Zhao, Xiao-Jing | Zhao, Jie | Sun, Xin | Liu, Ji-Kai | Wu, Bin
An efficient Lewis acid-promoted cascade reaction with dimethyl sulfoxide as a methylene source for the synthesis of Michael acceptors is reported. The key to developing this procedure is the selection of a mild base to modulate the equilibrium of various intermediates in order to drive the reaction forward to the formation of Michael acceptor and dimeric compound products. Extensive studies were performed to gain insight into a possible reaction mechanism.
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书目信息
Tetrahedron
ISSN
0040-4020
出版者
Elsevier Ltd
其它主题
Pummerer; Dimethyl sulfoxide; Dimethyl sulfoxide; Lewis acid; Dimerization; Dimerization; Michael acceptors
语言
英语
注释
Pre-press version
许可
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类型
Journal Article; Text
2024-02-27
MODS