Expanding the biological utility of bis-NHC gold(i) complexes through post synthetic carbamate conjugation
2019
Sen, Sajal | Li, Yue | Lynch, Vincent | Arumugam, Kuppuswamy | Sessler, Jonathan L. | Arambula, Jonathan F.
We report the synthesis of a novel hydroxyl-functionalised heteroleptic bis-NHC gold(i) complex that permits conjugation to various amines via carbamate bond formation. The resulting derivatives were studied in vitro using cell proliferation assays and fluorescent microscopic imaging of human cancer cell lines.
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书目信息
Chemical communications
卷
55
期
71
页码
10627
- 10630
ISSN
1364-548X
出版者
The Royal Society of Chemistry
其它主题
Neoplasm cells; Cell proliferation; Human cell lines; In vitro studies
语言
英语
许可
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类型
Text; Journal Article
2024-02-28
MODS
