Role of sphinogomyelin in cellular cholesterol homeostasis
1992
Rudney, H. | Gupta, A.K.
When the ratio of sphingomyelin to cholesterol in cellular membranes is disturbed, cellular cholesterol metabolism is modulated. This report reviews some of the disturbances in cholesterol biosynthesis which occur after treatment of cells in culture with exogenous sphingomyelinase from S. aureus. Treatment of LDL with the same sphingomyelinase preparation results in >90% reduction of the sphingomyelin content of the LDL particle and greatly enhances processing of LDL.
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书目信息
出版者
Elsevier B.V.
其它主题
Plasma membrane; Cholesterol metabolism; Regulation; Low density lipoprotein
语言
英语
注释
In the series analytic: regulation of isopentenoid metabolism / edited by w.d. nes, e.j. parish, and j.m. trzaskos. paper presented at the 201st national meeting, april 14-19, 1991, atlanta, georgia.
类型
Journal Article; Text
2024-02-29
MODS