Triterpenoids from the leaves of Ilex chinensis

Xia, Wen-Qi; Li, Ruo-Fei; Liu, Jia-Bao; Cui, Bao-Song; Hou, Qi; Sun, Hua; Li, Shuai

Triterpenoids from the leaves of Ilex chinensis

2018

Eleven previously undescribed compounds including two triterpenes, ilexchinenin A and ilexchinenin B, and nine triterpenoid saponins, ilexchinenosides A-I, along with twelve known triterpenoids were isolated from the leaves of Ilex chinensis Sims (Aquifoliaceae). Their structures were elucidated by spectroscopic analysis and comparison with known compounds. Furthermore, eight compounds exhibited significant inhibitory effects on NO production of lipopolysaccharide (LPS)-induced murine macrophages, while nine compounds exhibited potent hepatoprotective activity against N-acetyl-p-aminophenol (APAP)-induced HepG2 cell damage in in vitro assays.

اظهر المزيد [+]

الكلمات المفتاحية الخاصة بالمكنز الزراعي (أجروفوك)

aquifoliaceae ilex leaves lipopolysaccharides macrophages mice nitric oxide spectral analysis triterpenoids

المعلومات البيبليوغرافية

نُشرت في

Phytochemistry

المجلد 148 ترقيم الصفحات 113 - 121 الرقم التسلسلي المعياري الدولي (ردمد) 0031-9422

الناشر

Elsevier Ltd

مواضيع أخرى

Acetaminophen; Kvekdoptmygddk-vqkzpdjysa-n; Kibbhwocdoqdoi-bbbmabmqsa-n; Kssbxcgculzrbj-locxkcevsa-n; Ilex chinensis; Xvynahvlecpkks-amrvfusssa-n; Ucljwmgggkuvdb-kwqvfhkisa-n; Triterpenoid saponins; No production inhibitory activity; Human cell lines; Vvefvuhuxwxfnw-kwqvfhkisa-n; In vitro studies; Hkiolmfornwzky-yyqitphbsa-n; Bhsufixfuovbab-vqkzpdjysa-n; Cfcncbjrnlkpkt-yismkxidsa-n; Ioigmebsakpuiz-cfgdxzmhsa-n; Hepatoprotective activity; Jocaqcjunppkqb-kwqvfhkisa-n; Hepatoprotective effect

اللغة

إنجليزي

النوع

Journal Article; Text

في أجريس منذ: 2024-02-27

نوع الملف: MODS

مزود البيانات

تم تزويد هذا السجل من قبل National Agricultural Library

اكتشف مجموعة مزود البيانات هذا في أجريس

الروابط

DOI https://dx.doi.org/10.1016/j.phytochem.2018.01.008

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