Triterpenoids from the leaves of Ilex chinensis

Xia, Wen-Qi; Li, Ruo-Fei; Liu, Jia-Bao; Cui, Bao-Song; Hou, Qi; Sun, Hua; Li, Shuai

Triterpenoids from the leaves of Ilex chinensis

2018

Eleven previously undescribed compounds including two triterpenes, ilexchinenin A and ilexchinenin B, and nine triterpenoid saponins, ilexchinenosides A-I, along with twelve known triterpenoids were isolated from the leaves of Ilex chinensis Sims (Aquifoliaceae). Their structures were elucidated by spectroscopic analysis and comparison with known compounds. Furthermore, eight compounds exhibited significant inhibitory effects on NO production of lipopolysaccharide (LPS)-induced murine macrophages, while nine compounds exhibited potent hepatoprotective activity against N-acetyl-p-aminophenol (APAP)-induced HepG2 cell damage in in vitro assays.

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Mots clés AGROVOC

aquifoliaceae ilex leaves lipopolysaccharides macrophages mice nitric oxide spectral analysis triterpenoids

Informations bibliographiques

Publié dans

Phytochemistry

Volume 148 Pagination 113 - 121 ISSN 0031-9422

Editeur

Elsevier Ltd

D'autres materias

Acetaminophen; Kvekdoptmygddk-vqkzpdjysa-n; Kibbhwocdoqdoi-bbbmabmqsa-n; Kssbxcgculzrbj-locxkcevsa-n; Ilex chinensis; Xvynahvlecpkks-amrvfusssa-n; Ucljwmgggkuvdb-kwqvfhkisa-n; Triterpenoid saponins; No production inhibitory activity; Human cell lines; Vvefvuhuxwxfnw-kwqvfhkisa-n; In vitro studies; Hkiolmfornwzky-yyqitphbsa-n; Bhsufixfuovbab-vqkzpdjysa-n; Cfcncbjrnlkpkt-yismkxidsa-n; Ioigmebsakpuiz-cfgdxzmhsa-n; Hepatoprotective activity; Jocaqcjunppkqb-kwqvfhkisa-n; Hepatoprotective effect

Langue

anglais

Type

Journal Article; Text

Sur AGRIS depuis: 2024-02-27

Format: MODS

Fournisseur de données

Cette notice bibliographique a été fournie par National Agricultural Library

Découvrez la collection de ce fournisseur de données dans AGRIS

Liens

DOI https://dx.doi.org/10.1016/j.phytochem.2018.01.008

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