Triterpenoids from the leaves of Ilex chinensis

Xia, Wen-Qi; Li, Ruo-Fei; Liu, Jia-Bao; Cui, Bao-Song; Hou, Qi; Sun, Hua; Li, Shuai

Triterpenoids from the leaves of Ilex chinensis

2018

Eleven previously undescribed compounds including two triterpenes, ilexchinenin A and ilexchinenin B, and nine triterpenoid saponins, ilexchinenosides A-I, along with twelve known triterpenoids were isolated from the leaves of Ilex chinensis Sims (Aquifoliaceae). Their structures were elucidated by spectroscopic analysis and comparison with known compounds. Furthermore, eight compounds exhibited significant inhibitory effects on NO production of lipopolysaccharide (LPS)-induced murine macrophages, while nine compounds exhibited potent hepatoprotective activity against N-acetyl-p-aminophenol (APAP)-induced HepG2 cell damage in in vitro assays.

Mostrar más [+]

Palabras clave de AGROVOC

aquifoliaceae ilex leaves lipopolysaccharides macrophages mice nitric oxide spectral analysis triterpenoids

Información bibliográfica

Publicado en

Phytochemistry

Volumen 148 Paginación 113 - 121 ISSN 0031-9422

Editorial

Elsevier Ltd

Otras materias

Acetaminophen; Kvekdoptmygddk-vqkzpdjysa-n; Kibbhwocdoqdoi-bbbmabmqsa-n; Kssbxcgculzrbj-locxkcevsa-n; Ilex chinensis; Xvynahvlecpkks-amrvfusssa-n; Ucljwmgggkuvdb-kwqvfhkisa-n; Triterpenoid saponins; No production inhibitory activity; Human cell lines; Vvefvuhuxwxfnw-kwqvfhkisa-n; In vitro studies; Hkiolmfornwzky-yyqitphbsa-n; Bhsufixfuovbab-vqkzpdjysa-n; Cfcncbjrnlkpkt-yismkxidsa-n; Ioigmebsakpuiz-cfgdxzmhsa-n; Hepatoprotective activity; Jocaqcjunppkqb-kwqvfhkisa-n; Hepatoprotective effect

Idioma

Inglés

Tipo

Journal Article; Text

En AGRIS desde: 2024-02-27

Formato: MODS

Proveedor de Datos

Este registro bibliográfico ha sido proporcionado por National Agricultural Library

Descubra la colección de este proveedor de datos en AGRIS

Enlaces

DOI https://dx.doi.org/10.1016/j.phytochem.2018.01.008

Buscar en Google Scholar