Triterpenoids from the leaves of Ilex chinensis

Xia, Wen-Qi; Li, Ruo-Fei; Liu, Jia-Bao; Cui, Bao-Song; Hou, Qi; Sun, Hua; Li, Shuai

Triterpenoids from the leaves of Ilex chinensis

2018

Eleven previously undescribed compounds including two triterpenes, ilexchinenin A and ilexchinenin B, and nine triterpenoid saponins, ilexchinenosides A-I, along with twelve known triterpenoids were isolated from the leaves of Ilex chinensis Sims (Aquifoliaceae). Their structures were elucidated by spectroscopic analysis and comparison with known compounds. Furthermore, eight compounds exhibited significant inhibitory effects on NO production of lipopolysaccharide (LPS)-induced murine macrophages, while nine compounds exhibited potent hepatoprotective activity against N-acetyl-p-aminophenol (APAP)-induced HepG2 cell damage in in vitro assays.

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Ключевые слова АГРОВОК

aquifoliaceae ilex leaves lipopolysaccharides macrophages mice nitric oxide spectral analysis triterpenoids

Библиографическая информация

Опубликовано в

Phytochemistry

Том 148 Нумерация страниц 113 - 121 ISSN 0031-9422

Издатель

Elsevier Ltd

Другие темы

Acetaminophen; Kvekdoptmygddk-vqkzpdjysa-n; Kibbhwocdoqdoi-bbbmabmqsa-n; Kssbxcgculzrbj-locxkcevsa-n; Ilex chinensis; Xvynahvlecpkks-amrvfusssa-n; Ucljwmgggkuvdb-kwqvfhkisa-n; Triterpenoid saponins; No production inhibitory activity; Human cell lines; Vvefvuhuxwxfnw-kwqvfhkisa-n; In vitro studies; Hkiolmfornwzky-yyqitphbsa-n; Bhsufixfuovbab-vqkzpdjysa-n; Cfcncbjrnlkpkt-yismkxidsa-n; Ioigmebsakpuiz-cfgdxzmhsa-n; Hepatoprotective activity; Jocaqcjunppkqb-kwqvfhkisa-n; Hepatoprotective effect

Язык

Английский

Тип

Journal Article; Text

В АГРИСе с: 2024-02-27

Формат: MODS

Поставщик данных

Эту запись предоставил National Agricultural Library

Откройте коллекцию этого поставщика данных в AGRIS

Ссылки

DOI https://dx.doi.org/10.1016/j.phytochem.2018.01.008

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