Enterovirus replication: go with the (counter)flow

Nchoutmboube, Jules; Ford-Siltz, Lauren A.; Belov, George A.

Enterovirus replication: go with the (counter)flow

2015

Nchoutmboube, Jules | Ford-Siltz, Lauren A. | Belov, George A.

All (+)RNA viruses replicate on distinct membranous domains; however, how they induce and maintain their unique lipid composition is largely unknown. Two recent studies reveal that enteroviruses harness the PI4P–cholestrol exchange cycle driven by OSBP1 protein and PI4 kinase(s), and that blocking the dynamic lipid flow inhibits virus replication.

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Palabras clave de AGROVOC

enterovirus lipids virus replication

Información bibliográfica

Publicado en

Trends in microbiology

Volumen 23 Edición 4 Paginación 183 - 184 ISSN 0966-842X

Editorial

Elsevier Ltd

Otras materias

Cholesterol–pi4p exchange; Enterovirus replication organelles; Drug repurposing; Lipid trafficking; Lipid composition; Oxysterol binding protein (osbp)

Idioma

Inglés

Tipo

Journal Article; Text

En AGRIS desde: 2024-02-27

Formato: MODS

Proveedor de Datos

Este registro bibliográfico ha sido proporcionado por National Agricultural Library

Descubra la colección de este proveedor de datos en AGRIS

Enlaces

DOI http://dx.doi.org/10.1016/j.tim.2015.02.008

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